After the war, Audrey and her mother moved to London, where she studied ballet,
worked as a model, and in 1951, began acting in films, mostly in minor or supporting roles as Audrey Hepburn. She got into acting mainly to make money so that her mother would not have to work menial jobs to support them. Her first major performance was in the 1951 film The Secret People, in which she played a ballet dancer. Audrey had trained in ballet since childhood and won critical acclaim for her talent, which she showcased in the film. However, her ballet teachers had deemed her "too tall" to be a professional ballet dancer, since, at 5'7", she was taller than many of the male dancers. She was chosen to play the lead character in the Broadway play Gigi that opened on 24 November 1951.
She won a Theatre World Award for her debut performance, and it had a successful six-month run in New York City.
Audrey was then offered a starring role opposite Gregory Peck in the Hollywood motion picture, Roman Holiday. Peck saw her star quality and insisted she share top billing. For her performance, she won the 1953 Academy Award for Best Actress. Years later, when asked by Barbara Walters what her favorite film was, Audrey answered without hesitation, Roman Holiday, because it was the one that made her a star.
After Roman Holiday she filmed Sabrina with Humphrey Bogart and William Holden, with whom she had a brief romance. Many believe Holden considered Audrey to be the love of his life, and she would go on to appear with him again in the comedy Paris, When It Sizzles.
In 1954, Audrey went back to the stage playing the water sprite in Ondine in a performance with Mel Ferrer, whom she would wed later that year. For her performance in Ondine, Audrey was awarded the Tony Award for Best Actress (1954) which, coming only six weeks after her academy award for Roman Holiday, solidified her reputation as both a film and stage star.
Having become one of Hollywood's most popular box-office attractions, Audrey co-starred with other major actors such as Fred Astaire in Funny Face, Humphrey Bogart and Gary Cooper in Love in the Afternoon,George Peppard in Breakfast at Tiffany's, Cary Grant in the critically acclaimed hit Charade,
Rex Harrison in My Fair Lady, Peter O'Toole in How to Steal a Million, and Sean Connery in Robin and Marian.
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Many of these leading men became very close to her. Rex Harrison called Audrey his favorite leading lady; Cary Grant loved to humor her and once said, "all I want for Christmas is to make another movie with Audrey Hepburn;" and Gregory Peck became a lifelong friend. After her death, Peck went on camera and tearfully recited her favorite poem, "Unending Love." Some believe Bogart and Audrey did not get along, but this is untrue
Audrey had the reputation of being a humble, kind and charming person, who lived the philosophy of putting others before herself. She showed this side particularly towards the end of her life in her work for the United Nations Children's Fund (UNICEF). New Woman magazine called Audrey the most beautiful woman of all time, in a 2006 poll. She was ranked as the third greatest female star of all time by the American Film Institute.
Later she married Dr. Andrea Dotti. From time to time, she would appear on the silver screen. One film of note was Robin and Marian (1976) with Sean Connery in 1976. In 1988, Audrey became a special ambassador to the United Nations UNICEF fund helping children in Latin America and Africa, a position she retained until 1993. She was named to People's magazine as one of the 50 most beautiful people in the world.